Episode #1670
David Sinclair
Books mentioned
The Secret
Mentioned by Joe Rogan (host) · at 01:51:48 · ▶︎ Watch this moment on YouTube (approximate)
Amazon (opens in a new tab; affiliate link) Source: Transcript (podscripts.co)
Count Down
Mentioned by Joe Rogan (host) · at 01:59:09 · ▶︎ Watch this moment on YouTube (approximate)
Amazon (opens in a new tab; affiliate link) Source: Transcript (podscripts.co)
Timestamps are segment start times from the podscripts.co transcript of the audio release (includes ad reads), so they may differ from the video by a few minutes.
Harvard researcher David Sinclair joins Joe Rogan to examine biological aging and the possibility of extending healthy lifespans. They discuss diet, exercise, sleep, stress, environmental exposures, biological-age testing, gene engineering, and experimental interventions, while Sinclair reflects on mortality, personal growth, and his aging research.
What they talked about
- Lex Fridman's personality and skills
- Human evolution and tool-making
- Hyperbaric oxygen therapy and telomeres
- Metformin and hormesis for longevity
- NMN supplement and NAD metabolism
- Sleep optimization and temperature control
- Personalized medicine and epigenome
- David Sinclair's childhood motivation from grandmother
Data last updated · Report a mistake · How it works: mentions are pulled from public transcripts and episode descriptions, partly with AI-assisted extraction, so details and timestamps can be off.

