Episode #1267
Gary Taubes & Stephan Guyenet
Books mentioned
The Hungry Brain
Mentioned by Gary Taubes & Stephan Guyenet · at 00:01:02
Amazon (opens in a new tab; affiliate link) Source: Transcript (podscripts.co)
Good Calories, Bad Calories
Mentioned by Gary Taubes & Stephan Guyenet · at 01:08:37
Amazon (opens in a new tab; affiliate link) Source: Transcript (podscripts.co)
Metabolic Regulation
Mentioned by Gary Taubes & Stephan Guyenet · at 02:19:53
Amazon (opens in a new tab; affiliate link) Source: Transcript (podscripts.co)
The Case Against Sugar
Mentioned by Gary Taubes & Stephan Guyenet · at 02:36:51
Amazon (opens in a new tab; affiliate link) Source: Transcript (podscripts.co)
Timestamps are segment start times from the podscripts.co transcript of the audio release (includes ad reads), so they may differ from the video by a few minutes.
Journalist and low-carbohydrate diet advocate Gary Taubes and neuroscientist Stephan Guyenet examine competing explanations for obesity, focusing on brain regulation, hormones, insulin, fat storage, calorie intake, genetics, and the food environment. They also assess sugar, diabetes, physical activity, historical populations, overfeeding studies, malnutrition, and the quality and interpretation of nutrition research.
What they talked about
- Debate on the cause of obesity: brain regulation vs. insulin/hormones
- Genetics of obesity: brain-related genes vs. fat metabolism genes
- Role of leptin and set point theory in body fat regulation
- Overfeeding studies: calorie vs. macronutrient effects on fat gain
- Sugar and refined carbohydrates as drivers of obesity
- Pima and Kuna populations as case studies
- Non-alcoholic fatty liver disease and sugar reduction
- Caloric balance vs. hormonal model of weight gain
Data last updated · Report a mistake · How it works: mentions are pulled from public transcripts and episode descriptions, partly with AI-assisted extraction, so details and timestamps can be off.